Vigabatrin-Induced Visual Impairment

Abstract

Visual field examination, visual evoked potentials (VEPs), and electroretinography (ERG) were assessed in 24 children (ages 3.5 to 18 years; mean age 13.3 years) who had received vigabatrin as monotherapy (5 children) or adjunctive therapy (19) for epilepsy for more than 6 months (3.0 +/- 1.6 years), in a retrospective study at the Shaare Zedek Medical Center, Jerusalem, Israel.

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