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Published 2001 | Version v1.0.0
Journal Article Open

Thrombotic microangiopathy in the cancer patient

Abstract

Thrombotic microangiopathy, manifesting as thrombotic thrombocytopenic purpura (TTP) or hemolytic uremic syndrome, is a common complication in cancer patients. It shares the pathogenic microvascular occlusive lesion and many clinical manifestations as the classical TTP, but the spectrum of complications varies widely. Several subsets are seen, including a microangiopathic hemolyticanemia in advanced cancer, chemotherapeutic drug-associated microangiopathy and those with the transplant setting. The prognosis is not as favorable as in classical TTP. Anecdotal reports indicate that responses are seen with plasma exchange and with immunoadsorption.

Other

original_citation: Kwaan, H. C., & Gordon, L. I. (2001). Thrombotic microangiopathy in the cancer patient. Acta Haematol, 106(1-2), 52-56. https://doi.org/10.1159/000046589

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Additional details

Identifiers

PMID
11549777
ARK
ark:/c8131/g3gg68

Dates

Created
2001
When the item was originally created.