/**Note to users**/ Please cite the following study when using this data Cornelis et al. A genome-wide investigation of food addiction. Obesity 2016 https://doi.org/10.1002/oby.21476 See QC details in paper. No additional filters (i.e. imputation quality, MAF) were applied prior to generating sumstat file. ********************************************************************* * LD Score Regression (LDSC) * Version 1.0.0 * (C) 2014-2015 Brendan Bulik-Sullivan and Hilary Finucane * Broad Institute of MIT and Harvard / MIT Department of Mathematics * GNU General Public License v3 ********************************************************************* Call: ./ldsc.py \ --h2 yscore.sumstats.gz \ --ref-ld-chr eur_w_ld_chr/ \ --out yscore.h2 \ --w-ld-chr eur_w_ld_chr/ Beginning analysis at Thu Mar 1 15:04:32 2018 Reading summary statistics from yscore.sumstats.gz ... Read summary statistics for 1167735 SNPs. Reading reference panel LD Score from eur_w_ld_chr/[1-22] ... Read reference panel LD Scores for 1293150 SNPs. Removing partitioned LD Scores with zero variance. Reading regression weight LD Score from eur_w_ld_chr/[1-22] ... Read regression weight LD Scores for 1293150 SNPs. After merging with reference panel LD, 1163642 SNPs remain. After merging with regression SNP LD, 1163642 SNPs remain. Using two-step estimator with cutoff at 30. Total Observed scale h2: 0.0969 (0.0399) Lambda GC: 1.0075 Mean Chi^2: 1.0074 Intercept: 0.9895 (0.0058) Ratio < 0 (usually indicates GC correction). Analysis finished at Thu Mar 1 15:04:43 2018 Total time elapsed: 11.41s