Published 2019 | Version v1.0.0
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DNA Methylation of Individual Repetitive Elements in Hepatitis C Virus Infection-Induced Hepatocellular Carcinoma

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Description

The two most common repetitive elements (REs) in humans, long interspersed nuclear element-1 (LINE-1) and Alu element (Alu), have been linked to various cancers. Hepatitis C virus (HCV) may cause hepatocellular carcinoma (HCC) by suppressing host defenses, through DNA methylation that controls the mobilization of REs. We aimed to investigate the role of RE methylation in HCV-induced HCC (HCV-HCC).

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Funding

Fogarty International Center
Northwestern/Nigeria Research Training Program in HIV and Malignancies (NN-HAM) D43TW009575

Dates

Created
2019
When the item was originally created.